葡萄糖激酶 肠促胰岛素 医学 糖尿病 碳水化合物代谢 血糖性 胰岛素 升糖指数 过剩4 药理学 葡萄糖转运蛋白 内科学 内分泌学 2型糖尿病
作者
Soraya Sajadimajd,Gholamreza Bahrami,Maria Daglia,Seyed Mohammad Nabavi,Rozita Naseri,Mohammad Hosein Farzaei
出处
期刊:Food Reviews International [Informa]
日期:2019-03-19 卷期号:35 (6): 563-586 被引量:22
摘要
Background and aims: Diabetes mellitus is a chronic heterogenic disease characterized by the deregulation of the metabolism of insulin and glucose. The aim of this review has been to evaluate the efficacy of medical plant-based carbohydrates, excluding monosaccharides, to manage glycemic response in clinical trials.Methods: The range of literature presented was compiled by searching electronic databases, including Scopus, PubMed and Cochrane library, from their inception through to June 2018. Only clinical-based studies were considered for this review. Dietary carbohydrates were investigated, especially those containing fiber possessing beneficial effects in the management of hyperglycemia. The most common oligosaccharides, including xylooligosaccharide, isomaltooligosaccharide, fructooligosaccharide, galactooligosaccharide, and sucrose, were able to manage glycemic and insulin metabolism in clinical trials.Results: In light of 77 selected papers, several plant-based oligosaccharides and polysaccharides have been shown to significantly improve the management of glucose and insulin metabolism in healthy and diabetic patients.Conclusions: Oligosaccharides and polysaccharides derived from plants possess promising hypoglycemic potential, similar to and even more effective than current synthetic drugs, with no deleterious side effects.Abbreviations: AMPK: AMP-activated protein kinase; AX: Arabinoxylan; CAT: Catalase; CFDA: Chinese food and drug administration; DM: Diabetes mellitus; FBS, Fasting blood glucose; FDA: United States food and drug administration; FOS: Fructooligosaccharide; G6Pase: Glucose-6- phosphatase; GCK: glucokinase; GD: Gestational diabetes; GI: Glycemic index; GL: Glycemic load; Glut4: Glucose transporter 4; GOS: Glucooligosaccharide; GPx: glutathione peroxidase; GRAS: generally regarded as safe HCF: high-carbohydrate, high fiber diet; HNF1α: Hepatic nuclear factor 1 alpha, HNF4α: Hepatic nuclear factor 4α; HNF1β: Hepatic nuclear factor 1β; II: Insulinemic index; IOS: Isomaltooligosaccharides; KGM: Konjac glucomannan; LBP: L. barbarum polysaccharide; MODY: Maturity onset diabetes of the young; PECK: phosphoenolpyruvate carboxykinase; RDS: Rapidly digestible starch; RS: Resistant starch; SBOS: Soybean oligosaccharides; SDS: Slowly digestible starch; SNP: Single nucleotide polymorphism; SOD: Superoxide dismutase; T1DM: Type 1 diabetes; T2DM: Type 2 diabetes mellitus; TBARS: Thiobarbituric acid reactive substances; XOS: Xylooligo-saccharide.
求助该文献
最长约 10秒,即可获得该文献文件
科研通AI机器人已完成分析
对不起,本页面需要您登录以后才可查看
进入登录/注册页面
") }else{ var paper_html = ''; for (var i=0;i
'+this_paper['title']+'
'+ this_paper['authors'].join(", ")+'
'; } journal_html = ''; if (this_paper['journal']){ journal_html += ''+this_paper['journal']+''; } if (this_paper['publication_date']){ journal_html += ''+(this_paper['publication_date'].substring(0, 4))+''; } var biblio_html = ''; var biblio = this_paper['biblio']; if (biblio[0]){ biblio_html += biblio[0]; } if (biblio[1]){ biblio_html += " (" + biblio[1] + ")"; } if (biblio[2] || biblio[3]){ biblio_html += ": " + biblio[2] + "-" + biblio[3]; } if (biblio_html){ journal_html += ''+biblio_html+''; } if (this_paper['cited_by_count']){ journal_html += '被引量:'+this_paper['cited_by_count']+''; } paper_html += '' + journal_html + '
'; var ids_html = ''; if (this_paper['doi']){ ids_html += "DOI:" +this_paper['doi']+""; } if (this_paper['ids']){ ids_html += "PMID:" +this_paper['ids']+ ""; } if (ids_html){ paper_html += ''+ids_html+'
'; } if (i!=related_papers.length-1){ paper_html += ''; } paper_html += ''; } var old_html = $('.paper-related-content').html(); $('.paper-related-content').html(""); if (typeof old_html === 'string' && old_html.includes('科研通AI机器人正在分析抓取中')){ $('.paper-related-content ol').slideDown(); }else{ $('.paper-related-content ol').show(); } } } var old_html = $('.paper-related-content').html(); if (typeof old_html === 'string' && old_html.includes('科研通AI机器人正在分析抓取中')){ $.ajax({ type: 'POST', async: true, //表示请求是否异步处理 dataType: "json",//返回的数据类型 url: "/scholar/get-related-papers", data: { '_csrf': 'OC05vbEDUmvbV8SWhfoMCqmltFdot7pV8naavEiUCC5MX2zU4HYlBZJuoMOookRimO_kLgLmyxe3O8npL9pHZQ==', 'id':"3Q6vajnlE", 't':new Date().getTime() }, error: function (data) { $(".get-related-paper-status").html('对不起,发生错误,请请稍候再试如果长期遇到该问题,请通过底部客服中心反馈,谢谢') }, success: function (res) { if (res.code == 0) { //提交成功 render_related_papers(res.data); } else if (res.code == 1) { //出错 $(".get-related-paper-status").html('对不起,发生错误
错误提示:'+res.msg+'如果长期遇到该问题,请通过底部客服中心反馈,谢谢') } else { $(".get-related-paper-status").html('对不起,发生未知错误,请请稍候再试
如果长期遇到该问题,请通过底部客服中心反馈,谢谢') } } }); }else{ } return false; });
科研通智能强力驱动
Strongly Powered by AbleSci AI
我的文献求助列表 浏览历史
一分钟了解求助规则 | 捐赠本站 | 历史今天
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
- 实时播报
-
科研通AI5的应助被Xenia采纳,获得10
1秒前
-
科研通AI5上传了应助文件
1秒前
-
郭豪琪驳回了共享精神的应助
2秒前
-
木炭上传了应助文件
2秒前
-
酒吧舞男茜茜妈完成签到 ,获得积分10
2秒前
-
夏天来了发布了新的文献求助10
3秒前
-
华仔的应助被XY采纳,获得30
4秒前
-
LS完成签到,获得积分10
5秒前
-
脑洞疼的应助被xiaoxiao采纳,获得10
5秒前
-
Owen上传了应助文件
6秒前
-
张杠杠完成签到 ,获得积分10
6秒前
-
koala完成签到,获得积分10
6秒前
-
科目三的应助被烂橙子采纳,获得10
7秒前
-
zzzzyyxxxx发布了新的文献求助10
7秒前
-
留言发布了新的文献求助10
7秒前
-
细心的语蓉上传了应助文件
8秒前
-
等待的康乃馨完成签到,获得积分20
8秒前
-
身法马可波罗完成签到 ,获得积分10
9秒前
-
烟花上传了应助文件
9秒前
-
深情安青上传了应助文件
9秒前
-
稳重的八宝粥完成签到 ,获得积分10
9秒前
-
KKIII关闭了KKIII的文献求助
10秒前
-
传奇3上传了应助文件
10秒前
-
zwy完成签到,获得积分10
11秒前
-
Lee完成签到,获得积分10
11秒前
-
田様的应助被三度和弦采纳,获得10
12秒前
-
快乐凌寒的应助被cici采纳,获得10
12秒前
-
小蓝日记完成签到,获得积分10
13秒前
-
可爱的函函上传了应助文件
13秒前
-
tangsuyun完成签到 ,获得积分10
13秒前
-
Lig发布了新的文献求助30
14秒前
-
奶糖喵完成签到 ,获得积分10
14秒前
-
搜集达人上传了应助文件
15秒前
-
aigj发布了新的文献求助10
15秒前
-
Brave_1完成签到 ,获得积分10
16秒前
-
感动的安阳发布了新的文献求助30
16秒前
-
顾矜上传了应助文件
16秒前
-
dildil发布了新的文献求助10
17秒前
-
默默zzz发布了新的文献求助10
18秒前
-
田様上传了应助文件
19秒前
- 高分求助中
- Continuum Thermodynamics and Material Modelling 3000
- Production Logging: Theoretical and Interpretive Elements 2700
- Les Mantodea de Guyane Insecta, Polyneoptera 1000
- Conference Record, IAS Annual Meeting 1977 820
- England and the Discovery of America, 1481-1620 600
- Teaching language in context (Third edition) by Derewianka, Beverly; Jones, Pauline 550
- 電気学会論文誌D(産業応用部門誌), 141 巻, 11 号 510
- 热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
- 热门帖子
- 关注 科研通微信公众号,转发送积分 3581590
- 求助须知:如何正确求助?哪些是违规求助? 3151175
- 关于积分的说明 9486503
- 捐赠科研通 2853103
- 什么是DOI,文献DOI怎么找? 1568412
- 邀请新用户注册赠送积分活动 734683
- 科研通“疑难数据库(出版商)”最低求助积分说明 720724
今日热心研友
- 科研小民工 83 2220
- 迟大猫 115 1010
- Qi 94 1210
- iNk 63 450
- pluto 74 320
- VDC 35 530
- 小助 41 470
- cdercder 41 440
- 杳鸢 720
- HEIKU 39 290
- 求助 65
- 神说 33 320
- 自信项链 59
- 昏睡的凡桃 34 240
- 敬老院1号 560
- zzzq 56
- 不倦 550
- 斯文的寒风 19 280
- Hungrylunch 19 270
- S77 45
注:热心度 = 本日应助数 + 本日被采纳获取积分÷10
说明:该算法综合考虑我应助的数量和质量。但存在一定的滞后性,可能今天的应助到明天才被采纳,那这一部分的积分就要算到明天的排名中。
'; layer.open({ type: 0 ,shade: 0.1 ,btn:['关闭'] ,title: '排名介绍' ,content: html_content }); }); $('.hot-assisters .fly-panel-title a').bind('click',function () { $('.hot-assisters .fly-panel-title a').removeClass('layui-this'); $(this).addClass('layui-this'); var type = 'today'; $('.hot-assisters-item').hide(); if ($(this).hasClass('hot-today')){ type = 'today'; }else if ($(this).hasClass('hot-all')){ type = 'all'; }else if ($(this).hasClass('hot-week')){ type = 'week'; }else if ($(this).hasClass('hot-yesterday')){ type = 'yesterday'; }else if ($(this).hasClass('hot-month')){ type = 'month'; } $('.hot-assisters-' + type).show(); if (type != 'today' ){ if (($('.hot-assisters-'+type).html()).trim()==''){ $('.hot-assisters-'+type) .html('
正在获取,请稍候
'); $.ajax({ type: 'POST', async: true, //表示请求是否异步处理 dataType: "json",//返回的数据类型 url: "https://www.ablesci.com/user/hot-assisters", data:{ '_csrf': 'OC05vbEDUmvbV8SWhfoMCqmltFdot7pV8naavEiUCC5MX2zU4HYlBZJuoMOookRimO_kLgLmyxe3O8npL9pHZQ==', 'type':type }, error: function (data) { $('.hot-assisters-'+type) .html('
对不起,发生错误
'); }, success: function (res) { if (res.code == 0) { //提交成功 var html_str = '
- '; for (i=0;i<(res.data).length;i++){ html_str = html_str + "
- " + (res.data[i].online==true?'':"") + ""+ "" + "" + res.data[i].nickname + "" + res.data[i].c + "次应助" + "" + " "; } html_str = html_str + '
'; $('.hot-assisters-'+type).html(html_str); } else if (res.code == 1) { $('.hot-assisters-'+type) .html('
'+res.msg+'
'); } else { $('.hot-assisters-'+type) .html('
对不起,发生未知错误
'); } } }); } } }) })